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A dietary intervention comprising whole blueberries and soluble fiber (specifically partially hydrolyzed guar gum) investigated for its potential to reduce metabolic complications in high-risk pregnancies. The combination aims to improve maternal antioxidant status and adipocyte function in women with obesity. Clinical trial results have demonstrated that this supplementation significantly increases maternal serum glutathione and antioxidant capacity while decreasing biomarkers of oxidative stress (malondialdehyde) and adipocyte dysfunction (plasminogen activator inhibitor-1 and visfatin). The intervention is also associated with reduced excess gestational weight gain and improved blood glucose levels.
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