Drug intelligence / Profile preview

BOC-GAMMA-D-GLU-L-LYS(CBZ)-D-BOROALA

Development stage
Unknown
Modality
Peptides, Small Molecules
01

Overview

BOC-GAMMA-D-GLU-L-LYS(CBZ)-D-BOROALA is a synthetic small molecule dipeptide derivative containing a boronic acid moiety. It is classified as an experimental compound and has not been approved for clinical use. The structure features protected amino acids, including gamma-D-glutamic acid, L–lysine with a carbobenzoxy (CBZ or Z-) group, and D-boroalanine. The presence of the boronic acid group suggests potential activity as a protease inhibitor or enzyme modulator, but no specific mechanism of action or therapeutic indication has been established in the literature[2][3][7]. There are no known clinical trials or approved uses for this compound.

Other names
Boc-gamma-D-glu-L-lys(cbz)-D-boroala(2S)-4-(((1S)-5-(((benzyloxy)carbonyl)amino)-1-(((1S)-1-(dihydroxyboranyl)ethyl)carbamoyl)pentyl)carbamoyl)-2-(((tert-butoxy)carbonyl)amino)butanoic acidN-(tert-butoxycarbonyl)-L-gamma-glutamyl-N~6~-[(benzyloxy)carbonyl]-N-[(1S)-1-(dihydroxyboranyl)ethyl]-L-lysinamide
02

Targets

PBP (Penicillin-binding protein family)

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