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bone marrow-derived mesenchymal stem cells (Guangzhou Institute of Respiratory Health)
- Development stage
- Unknown
- Lead developer
- Guangzhou Institute of Respiratory Disease
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Bone marrow-derived mesenchymal stem cells (BM-MSCs) are an investigational cell therapy developed by the Guangzhou Institute of Respiratory Disease for the treatment of severe COVID-19. These multipotent cells are administered intravenously and function primarily through their potent immunomodulatory and anti-inflammatory properties. By inhibiting the overactivation of pathogenic T cells and inflammatory monocytes, BM-MSCs help to mitigate the 'cytokine storm' and systemic inflammation that drive acute respiratory distress syndrome (ARDS) in COVID-19 patients. Additionally, they are thought to promote lung tissue repair and regeneration, potentially improving survival and recovery in critically ill individuals.
- Other names
- mesenchymal stem cells-Guangzhou Institute of Respiratory Disease-COVID-19MSCsMesenchymal stem cells
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