Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
bone marrow-derived mesenchymal stem cells + hormone replacement therapy
- Development stage
- Unknown
- Lead developer
- Bioinova
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intraovarian, Intrauterine, Intravenous, Oral, Transdermal, Vaginal
01
Overview
A combination therapy approach that utilizes bone marrow-derived mesenchymal stem cells (BMSCs) alongside hormone replacement therapy (HRT). This therapeutic strategy aims to address both the tissue regeneration and hormonal aspects of female reproductive disorders, particularly premature ovarian insufficiency (POI). The mesenchymal stem cells work to restore ovarian reproductive and endocrine functions through mechanisms including controlling differentiation, promoting angiogenesis, regulating fibrosis, inhibiting apoptosis, enhancing paracrine effects, suppressing inflammation, and modulating the immune system. The hormone replacement component helps manage menopausal symptoms and hormonal imbalances.
- Other names
- autologous bone marrow-derived mesenchymal stem cells + HRTMSC + HRT
02
Targets
ER (Estrogen receptor)PR (Progesterone receptor)
Beyond the preview
Go deeper on bone marrow-derived mesenchymal stem cells + hormone replacement therapy.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on bone marrow-derived mesenchymal stem cells + hormone replacement therapy.