boswellia + UC-II

Boswellia + UC-II is a **combination dietary supplement** containing Boswellia serrata extract and undenatured type II collagen (UC-II). Both ingredients are known for supporting joint health and mobility. **Boswellia serrata** contains boswellic acids that inhibit pro-inflammatory enzymes (notably 5-lipoxygenase), thereby reducing leukotriene-mediated inflammation in joints. **UC-II (undenatured type II collagen)** is derived from chicken sternum cartilage and works via *oral tolerance*: it interacts with Peyer’s patches in the gut, inducing the generation of regulatory T cells and subsequent secretion of anti-inflammatory cytokines (e.g., TGF-beta, IL-4, IL-10), modulating immune responses to joint collagen. The combination has demonstrated efficacy in improving mobility and reducing pain and stiffness in humans and dogs with osteoarthritis, with no significant adverse effects reported in trials[1][2][3][6][7][8].

Brand names

Doctor's Best Boswellia with UC-II

Other names

boswellia with UC-IIboswellia serrata + UC-IIboswellia + undenatured type II collagen