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brimonidine tartrate + sodium hyaluronate
- Development stage
- Phase 3
- Lead developer
- Bausch + Lomb
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
This is a combination ophthalmic preparation containing **brimonidine tartrate**, a relatively selective alpha-2 adrenergic receptor agonist, and **sodium hyaluronate**, a viscoelastic polymer commonly used for its lubricating and tear film-stabilizing effects. **Brimonidine tartrate** lowers intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. **Sodium hyaluronate** acts as an ocular lubricant, improving comfort and surface healing for dry or irritated eyes. This combination may be used in the management of open-angle glaucoma or ocular hypertension (by brimonidine) and to address symptoms of ocular surface discomfort (by sodium hyaluronate).
- Other names
- BTOS-HA
02
Targets
ADRA2A (α2A)
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