Drug intelligence / Profile preview

brinzolamide + latanoprost

Development stage
Preclinical
Lead developer
Novartis
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

brinzolamide + latanoprost is a combination ophthalmic drug used for the treatment of glaucoma and ocular hypertension. Brinzolamide is a **carbonic anhydrase inhibitor** that lowers intraocular pressure by inhibiting the enzyme carbonic anhydrase in the ciliary body, decreasing aqueous humor production. Latanoprost is a **prostaglandin F2-alpha (FP) receptor agonist** that increases the uveoscleral outflow of aqueous humor. Their complementary mechanisms offer improved 24-hour intraocular pressure control compared to monotherapy, and studies have confirmed superior efficacy for controlling both diurnal and nocturnal eye pressure in patients[1][3][6].

Other names
Latanoprost 0.005% / Brinzolamide 1% fixed-dose combinationLatanoprost 50 μg/mL / Brinzolamide 10 mg/mLLatanoprost + Brinzolamide combination
02

Targets

PTGFR (Prostaglandin F2 alpha receptor)CA (Carbonic anhydrase)

Beyond the preview

Go deeper on brinzolamide + latanoprost.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on brinzolamide + latanoprost.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call