bromhexine + guaifenesin

Bromhexine + guaifenesin is an oral fixed-dose combination of the mucolytic agent bromhexine and the expectorant guaifenesin, used for the symptomatic treatment of productive (chesty) cough and respiratory conditions characterized by excessive, viscous mucus such as acute and chronic bronchitis and other bronchopulmonary disorders.[2][3][8][9] Bromhexine depolymerizes and thins mucopolysaccharide fibers in bronchial secretions, reducing mucus viscosity and facilitating ciliary clearance, while guaifenesin increases the volume and decreases the adhesiveness and surface tension of bronchial secretions, making mucus easier to mobilize and expectorate.[2][3][4][9] Together, this small‑molecule combination enhances mucociliary clearance and converts unproductive cough into a more productive one without opioid-induced sedation, and is marketed in multiple countries in various over-the-counter and prescription cough and cold products, particularly as syrups and oral liquids.[2][3][8][9]

Brand names

Chesty Cough ForteDuro-Tuss Chesty Cough Liquid ForteDimetapp Chesty Cough ElixirChemists’ Own Chesty Cough oral liquid