brompheniramine + pseudoephedrine + dextromethorphan

**Brompheniramine + pseudoephedrine + dextromethorphan** is a fixed-dose combination medication containing three active ingredients: an antihistamine (brompheniramine), a decongestant (pseudoephedrine), and a cough suppressant (dextromethorphan). It is used for the symptomatic relief of upper respiratory symptoms associated with allergies or the common cold, including cough, nasal congestion, runny nose, sneezing, and watery eyes[1][2][3]. **Mechanism of action:** *Brompheniramine* is an H1-receptor antagonist that blocks histamine at H1 receptors on effector cells in the respiratory tract, blood vessels, and GI tract. It also has anticholinergic effects that help dry secretions[4]. *Pseudoephedrine* acts as a sympathomimetic agent primarily on alpha-sympathetic receptors to cause vasoconstriction in nasal mucosa, reducing swelling and congestion[4]. *Dextromethorphan* acts centrally on the medullary cough center to suppress the cough reflex without analgesic or addictive properties[4]. The combination does not treat infections but provides short-term relief from allergy or cold symptoms.

Brand names

Bromfed DMAnaplex DMAndehist DMAndehist DM NRBrom/PSE/DM CoughBromaline DMBromatane DXBromaxefed DM RFBromdex DBrometane DXBromfed-DMBromophed DXBromphenex DMBromplex DMBrotapp-DMBroveX PSB DMCarbofed DMCardec DMDallergy DMDecon DMDimetane DXDimetapp Children's DM Cold and CoughDynatussEndaCof-DMLoHist PSB DMMyphetane DXNeo DMPBM AllergyQ-Tapp DMRobitussin Cough and AllergyRondamine DMRondec DMSildec DMTuss Mine DM

Other names

brompheniramine + pseudoephedrine + dextromethorphanbrompheniramine maleate + pseudoephedrine HCl + dextromethorphan HBr