Drug intelligence / Profile preview

buddha's hand fruit

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Buddha's Hand fruit, scientifically known as Citrus medica var. sarcodactylis, is a unique citrus fruit primarily valued for its aromatic rind and distinctive finger-like segments. Unlike most citrus fruits, it contains little to no pulp or juice. It has a long history of use in traditional Chinese medicine (TCM), where it is known as Foshou. In TCM, it is used to regulate Qi, harmonize the stomach, expel phlegm, and alleviate conditions such as liver depression, qi stagnation, digestive issues (nausea, vomiting, bloating, stomach pain, poor appetite), respiratory problems (coughs, asthma, bronchitis), and inflammation. The fruit contains various bioactive compounds including limonoids, flavonoids, coumarins, terpenoids, glycosides, polysaccharides, and essential oils (like limonene and γ-terpinene), which contribute to its reported antioxidant, anti-inflammatory, analgesic, expectorant, antispasmodic, and gastroprotective properties. While its traditional uses are well-documented, modern scientific research on its efficacy in humans is still limited, though some studies have explored its potential in areas like anti-cancer, hypolipidemic, immunosuppressive, antimicrobial, antiviral, and hypoglycemic effects. It is also used in culinary applications for its zest and aroma, and in perfumery and aromatherapy.

Other names
佛手FoshouFingered CitronCitrus medica var. sarcodactylisCitrus medica

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