Drug intelligence / Profile preview

budesonide + indacaterol

Development stage
Preclinical
Lead developer
Zydus Lifesciences
Modality
Small Molecules
Administration
Inhalation
01

Overview

**Budesonide + indacaterol** is a combination drug consisting of **budesonide**, an inhaled corticosteroid that reduces airway inflammation, and **indacaterol**, a long-acting beta-2 adrenergic agonist (**LABA**) that acts as a bronchodilator by relaxing airway smooth muscle. This combination is formulated for the maintenance treatment of airway obstructive diseases such as **chronic obstructive pulmonary disease (COPD)**. Budesonide suppresses inflammatory responses in the lungs, while indacaterol provides sustained bronchodilation to improve airflow. This formulation is typically administered by inhalation for long-term management and symptom control, notably in COPD—though while fixed-dose combinations of budesonide with formoterol are widely marketed, a fixed-dose budesonide + indacaterol combination is not an established, widely approved commercial product as of the latest searches[5].

Other names
budesonide and indacaterol free combinationbudesonide/indacaterol
02

Targets

GR (Glucocorticoid receptor)CYP3A5 (Cytochrome P450 family 3 subfamily A member 5)CYP3A7 (Cytochrome P450 3A7)CYP3A4 (Cytochrome P450 3A4)ADRB2 (β2)

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