bupivacaine + sufentanil (0.1% bupivacaine + 5 µg sufentanil)

B1S5 is a specific combination of 0.1% bupivacaine and 5 µg sufentanil, formulated in 15 mL, used for epidural analgesia during labor. Bupivacaine is a local anesthetic that blocks nerve impulses by decreasing the permeability of neuronal membranes to sodium ions, thereby inhibiting depolarization. Sufentanil is a potent synthetic opioid analgesic that acts as an agonist at mu-opioid receptors in the central nervous system, leading to pain relief and sedation. This combination aims to provide effective analgesia with minimal side effects during labor.

Other names

0.1% bupivacaine and 5 μg sufentanilbupivacaine 0.1% + sufentanil 5 mcg