Drug intelligence / Profile preview

bupivacaine hydrochloride + isopropyl alcohol + povidone-iodine + lidocaine

Development stage
Unknown
Lead developer
Advanced Rx of Tennessee
Modality
Small Molecules
Administration
Parenteral, Topical
01

Overview

**Bupivacaine hydrochloride + isopropyl alcohol + povidone-iodine + lidocaine** is a procedural local anesthesia combination kit marketed as **Point of Care LM 2.2**. The kit combines two amide-type small-molecule local anesthetics, bupivacaine hydrochloride and lidocaine hydrochloride, with topical antiseptic skin-preparation components, isopropyl alcohol and povidone-iodine. Its intended use is to facilitate local or regional anesthesia for surgical, diagnostic, and therapeutic procedures, with the anesthetic effect mediated primarily by reversible blockade of voltage-gated sodium channels in peripheral nerves, thereby preventing initiation and conduction of nerve impulses. The antiseptic components are used for injection-site preparation rather than providing the anesthetic pharmacology. Public context provided indicates distribution by AuroMedics Pharma and use in anesthesia.

Brand names
Point of Care LM 2.2
Other names
bupivacaine hydrochloride + isopropyl alcohol + povidone-iodine + lidocainebupivacaine hydrochloride + lidocaine hydrochloride + isopropyl alcohol + povidone-iodine
02

Targets

NaV (Voltage-gated sodium channels)Kir (Inward-rectifier potassium channels)

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