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Bushen Huazhuo Formula (Xiyuan Hospital)

Development stage
Unknown
Lead developer
Xiyuan Hospital
Administration
Oral
01

Overview

Bushen Huazhuo Formula is a Traditional Chinese Medicine (TCM) herbal composition developed by Xiyuan Hospital of the China Academy of Chinese Medical Sciences. It is specifically indicated for the treatment of mild to moderate Alzheimer's disease in patients presenting with the 'Kidney Deficiency and Phlegm Obstruction' syndrome pattern. The formula is intended to improve cognitive performance and daily functioning by tonifying kidney essence and clearing pathological phlegm, which are central to the TCM understanding of dementia. It is currently being studied in clinical trials to evaluate its efficacy and safety profile relative to established performance goals.

Other names
Bushen Huazhuo RecipeBushen Huazhuo Decoction
02

Targets

ESR1 (ERα)VEGFA (Vascular endothelial growth factor A)JNK (Mitogen-activated protein kinase kinase kinase family)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)EGFR T790M (Epidermal growth factor receptor T790M mutant)IL-6 (Interleukin 6)

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