Drug intelligence / Profile preview

bushen huoxue (Yueyang Hospital of Integrated Traditional Chinese and Western Medicine)

Development stage
Unknown
Lead developer
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
Administration
Oral
01

Overview

Bushen Huoxue (also known as Bushen Huoxue Fang or Decoction) is a Traditional Chinese Medicine (TCM) herbal formula developed and studied by the Yueyang Hospital of Integrated Traditional Chinese and Western Medicine and the Shanghai University of Traditional Chinese Medicine. The formula is designed based on the TCM therapeutic principles of "Bushen" (tonifying the kidney) and "Huoxue" (invigorating blood circulation), which are traditionally applied to treat reproductive and endocrine disorders. Its primary clinical focus is the treatment of premature ovarian failure (POF) and diminished ovarian reserve. Research suggests that the formula may help regulate serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2), while potentially improving ovarian blood flow and reducing apoptosis in granulosa cells. It is typically administered as an oral decoction or in granule form.

Brand names
bushen yangxue prescription
Other names
Bushen Huoxue FangBushen Huoxue DecoctionBushen Huoxue PrescriptionBu Shen Huo Xue Fang
02

Targets

PSMD10 (Proteasome 26S subunit non-ATPase 10)FSHR (Follicle-stimulating hormone receptor)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)CCND1 (Cyclin D1)HIF-α (Hypoxia-inducible factor alpha)

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