Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
busulfan + cyclosporine + fludarabine + mycophenolate mofetil
- Development stage
- Unknown
- Lead developer
- GSK
- Modality
- Small Molecules
- Administration
- Intravenous, Oral
01
Overview
This is a combination drug regimen used in hematopoietic stem cell transplantation (HSCT). The combination includes busulfan (an alkylating agent), cyclosporine (a calcineurin inhibitor), fludarabine (a purine nucleoside analog), and mycophenolate mofetil (an immunosuppressant). This regimen is primarily used as a reduced-intensity conditioning (RIC) regimen before stem cell transplantation, with cyclosporine and mycophenolate mofetil specifically serving as prophylaxis against graft-versus-host disease (GVHD). The combination is used in patients with various hematologic malignancies receiving allogeneic transplantation, particularly from unrelated donors.
02
Targets
CN (Calcineurin)DNADNA polymerase familyIMPDH (Inosine-5'-monophosphate dehydrogenase 1)
Beyond the preview
Go deeper on busulfan + cyclosporine + fludarabine + mycophenolate mofetil.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on busulfan + cyclosporine + fludarabine + mycophenolate mofetil.