Drug intelligence / Profile preview

cabergoline + hydroxyethyl starch

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Intravenous
01

Overview

A combination therapy approach using cabergoline (a dopamine receptor agonist) and hydroxyethyl starch (a plasma volume expander) for the prevention of ovarian hyperstimulation syndrome (OHSS) in women undergoing in vitro fertilization. Cabergoline works by inhibiting prolactin secretion and reducing vascular permeability, while hydroxyethyl starch is administered as an intravenous solution to maintain blood volume.

02

Targets

DRD3 (Dopamine receptor D3)DRD4 (Dopamine D4 Receptor)DRD2 (Dopamine D2 Receptor)ADRA1 (Alpha-1 adrenergic receptor family)DRD1 (Dopamine D1 Receptor)5-HT2 (5-HT2 receptor family)

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