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cadonilimab + pulocimab + paclitaxel is a combination regimen used in oncology clinical research. **Cadonilimab** is a bispecific monoclonal antibody targeting both PD-1 and CTLA-4, engineered as an immunotherapy to enhance anti-tumor immune responses. **Pulocimab** is a monoclonal antibody that targets LAG-3, another immune checkpoint, also designed for cancer immunotherapy. **Paclitaxel** is a chemotherapeutic agent that stabilizes microtubules, disrupting mitosis and causing cell death in rapidly dividing tumor cells[1][2][3]. This combination regimen is under development for solid tumor malignancies, aiming to synergistically block multiple immune checkpoints while directly targeting tumor cells with cytotoxic chemotherapy.
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