Drug intelligence / Profile preview

caffeine + L-theanine + vinpocetine + L-tyrosine + pyridoxine + cobalamin

Development stage
Unknown
Lead developer
Taiyo Kagaku
Modality
Small Molecules
Administration
Oral
01

Overview

A combination product containing **caffeine**, **L-theanine**, **vinpocetine**, **L-tyrosine**, **pyridoxine** (vitamin B6), and **cobalamin** (vitamin B12). This formulation combines stimulatory, neuroprotective, and cognitive-enhancing ingredients. - **Caffeine** is a central nervous system stimulant that works primarily as an adenosine receptor antagonist, promoting alertness and focus. - **L-theanine** is an amino acid found in tea that promotes relaxation, modulates neurotransmitter activity (notably GABA, serotonin, and dopamine), and augments alpha brain waves. - **Vinpocetine** is a synthetic derivative of the alkaloid vincamine, used for its potential neuroprotective effects and believed to enhance cerebral blood flow. - **L-tyrosine** is a precursor to catecholamine neurotransmitters (dopamine, norepinephrine, and epinephrine) and may enhance cognitive function under stress. - **Pyridoxine** (vitamin B6) is involved in neurotransmitter synthesis and overall brain health. - **Cobalamin** (vitamin B12) is important for nerve function and neurological health. The combined formulation targets cognitive performance, attention, mood, and may offer neuroprotective support. This combination is not a registered pharmaceutical; rather, it is formulated as a dietary supplement stack designed for acute and chronic cognitive enhancement in healthy individuals, especially under stress or sleep deprivation.

02

Targets

ADORA2A (Adenosine A₂A Receptor)ADORA1 (Adenosine receptor A1 subtype)NaV (Voltage-gated sodium channels)AMPAR (AMPA receptor)PDE1 (Phosphodiesterase 1)Kainate-type ionotropic glutamate receptorNMDAR (Glutamate receptor ionotropic, NMDA)

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