calcipotriene + dimethicone

Calcipotriene + dimethicone is a **topical combination product** containing calcipotriene, a synthetic vitamin D3 analogue, and dimethicone, an emollient. **Calcipotriene** acts on the vitamin D receptor to reduce keratinocyte proliferation and modulate immune responses in the skin, leading to improvement in conditions like plaque psoriasis. **Dimethicone** is an inert silicone-based oil used to moisturize and protect the skin, enhancing the barrier function and reducing irritation. This combination is formulated as a topical cream, primarily indicated for the treatment of plaque psoriasis, with calcipotriene responsible for the primary pharmacological action and dimethicone serving to improve tolerability and skin hydration[7][8].

Brand names

NUDERMRXPAK 60NUDERMRXPAK60NUDERMRXPAK-60