calcium + vitamin D + active vitamin D

calcium + vitamin D + active vitamin D is a therapeutic combination regimen developed by Aarhus University Hospital for the management and prevention of postoperative hypoparathyroidism following total thyroidectomy. This regimen includes high-dose elemental calcium, vitamin D (cholecalciferol), and active vitamin D (such as calcitriol or alfacalcidol). The mechanism involves providing a direct source of calcium while the vitamin D components, particularly the active form, bind to the Vitamin D Receptor (VDR) to enhance intestinal calcium absorption and maintain serum calcium levels, effectively bypassing the requirement for parathyroid hormone (PTH) which is often deficient or absent post-surgery.

Other names

high-dose calcium, vitamin D, and active vitamin D supplementationhigh-dose calcium (400 mg x 4), vitamin D (19 mikg x 4), and active vitamin D supplementation (2 mikg x 2)