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calcium acetate + magnesium carbonate (Fresenius Medical Care)
- Development stage
- Unknown
- Lead developer
- Fresenius Medical Care
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Calcium acetate + magnesium carbonate (marketed under the brand name OsvaRen) is an oral, fixed-dose combination phosphate binder containing calcium acetate and magnesium carbonate. It is indicated for the treatment of hyperphosphatemia associated with chronic kidney disease (CKD) in patients undergoing dialysis (hemodialysis or peritoneal dialysis). By combining calcium and magnesium, the drug lowers the required calcium intake compared to pure calcium-based binders, thereby reducing the risk of hypercalcemia and vascular calcification, while maintaining high phosphate-binding capacity. In the gastrointestinal tract, calcium and magnesium ions bind dietary phosphate to form insoluble complexes that are excreted in the feces.
- Brand names
- Atecal-PlusOsvaRenRenepho
- Other names
- CaMgcalcium acetate and magnesium carbonatecalcium acetate/magnesium carbonatecalcium/magnesium phosphate binder
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