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calcium carbonate + calcitriol + menaquinone-7
- Development stage
- Unknown
- Lead developer
- Medimax Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
CALZONE-K27 is a fixed-dose combination nutritional supplement developed and marketed by Medimax Pharmaceuticals. It is primarily indicated for the management of calcium deficiency and bone-related disorders such as osteoporosis and osteomalacia. The formulation typically contains calcium carbonate, which provides elemental calcium for bone mineralization; calcitriol, the active form of vitamin D3 that enhances intestinal calcium absorption by acting as a vitamin D receptor agonist; and menaquinone-7 (vitamin K2-7), which serves as a cofactor for the carboxylation of osteocalcin. This synergistic combination ensures that calcium is effectively absorbed and integrated into the bone matrix while minimizing the risk of vascular calcification.
- Brand names
- CALZONE-K27CALZONE-K-27CALZONE-K 27
- Other names
- Calcium Carbonate + Calcitriol + Vitamin K2-7Calcium Carbonate, Calcitriol and Vitamin K2-7 Capsules
02
Targets
VDR (Vitamin D receptor)
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