Drug intelligence / Profile preview

calcium carbonate + fluoride

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

**Calcium carbonate + fluoride** is an oral fixed-dose mineral supplement combination represented by the marketed product Florical, which supplies calcium carbonate from oyster shell and sodium fluoride in a capsule. Calcium provides an absorbable source of calcium for normal skeletal mineralization and neuromuscular physiology, while fluoride can incorporate into hydroxyapatite-containing mineral to support formation of more acid-resistant fluorapatite in dental enamel and may affect bone mineralization. Florical is listed by its manufacturer as a dietary supplement, not as an FDA-approved prescription drug; its current label specifies 364 mg calcium carbonate and 8.3 mg sodium fluoride per capsule, equivalent to 145 mg calcium and 3.75 mg fluoride. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=70faa127-b6c8-493c-9aa9-16885bbfca80))

Brand names
Florical
Other names
calcium carbonate + sodium fluoridefluoride + calcium carbonatesodium fluoride + calcium carbonate

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