Drug intelligence / Profile preview

calcium carbonate + magnesium carbonate

Development stage
Unknown
Lead developer
Nephro-Tech
Modality
Small Molecules
Administration
Oral
01

Overview

Calcium carbonate + magnesium carbonate is a fixed-dose combination of mineral salts used primarily as a phosphate binder and an antacid. In patients with chronic kidney disease (CKD), it is utilized to manage hyperphosphatemia by binding to dietary phosphate in the gastrointestinal tract, forming insoluble calcium and magnesium phosphate complexes that are subsequently excreted. As an antacid, the combination provides rapid relief from symptoms of dyspepsia and heartburn by neutralizing excess gastric hydrochloric acid. This formulation is often preferred in renal care to provide phosphate control while potentially reducing the total calcium load compared to calcium-only binders and avoiding aluminum-based agents.

Brand names
MagneBind 300MagneBind300MagneBind-300RennieRemegelMagneBind 400MagneBind400MagneBind-400
Other names
calcium carbonate and magnesium carbonate

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