Drug intelligence / Profile preview

calcium carbonate + colecalciferol (Thornton & Ross)

Development stage
Unknown
Lead developer
Thornton & Ross
Modality
Small Molecules
Administration
Oral
01

Overview

Accrete-D is a fixed-dose combination product containing calcium carbonate and colecalciferol (vitamin D3). It is developed and marketed by Thornton & Ross (a STADA company) primarily for the prevention and treatment of calcium and vitamin D deficiency in the elderly, as well as an adjunct to specific osteoporosis treatments. Calcium is a critical mineral for bone health, and its carbonate salt provides a high concentration of elemental calcium. Colecalciferol is converted in the body to its active form, calcitriol, which binds to the vitamin D receptor (VDR) to increase the intestinal absorption of calcium and maintain adequate serum calcium and phosphate concentrations for bone mineralization.

Brand names
Accrete-D
Other names
calcium and vitamin D3Accrete-D3Accrete-D-3Accrete-D 3
02

Targets

VDR (Vitamin D receptor)

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