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calcium chloride + magnesium chloride + dextrose monohydrate + sodium chloride + sodium lactate

Development stage
Approved
Lead developer
Fresenius Medical Care
Modality
Small Molecules
Administration
Intraperitoneal
01

Overview

**Calcium chloride + magnesium chloride + dextrose monohydrate + sodium chloride + sodium lactate** is a multi-electrolyte **peritoneal dialysis solution** marketed under the brand **DELFLEX** for the treatment of **chronic kidney failure** in patients maintained on peritoneal dialysis. It is a sterile, non-pyrogenic aqueous solution administered **intraperitoneally**, not intravenously. **Dextrose monohydrate** functions as the principal osmotic agent, creating an osmotic gradient across the peritoneal membrane to promote ultrafiltration and removal of excess water and uremic solutes, while **sodium, chloride, lactate, calcium, and magnesium** help maintain electrolyte and acid-base balance during dialysis. DELFLEX is available in multiple dextrose strengths and electrolyte compositions, including low magnesium and low calcium variants; the product was initially approved in the United States in **1984**, with a low magnesium/low calcium formulation approved in **1992**.

Brand names
DELFLEX
Other names
dextrose peritoneal dialysis solutionperitoneal dialysis solution

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