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calcium chloride + magnesium chloride + potassium chloride + povidone + sodium bicarbonate + sodium chloride

Development stage
Unknown
Lead developer
Medpolymer
Modality
Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration
Intravenous
01

Overview

Neohemodez is an approved, intravenously administered plasma-substituting and detoxifying infusion solution. It is formulated with low-molecular-weight povidone (polyvinylpyrrolidone, molecular weight 8,000 ± 2,000) combined with essential electrolytes (sodium chloride, potassium chloride, calcium chloride, magnesium chloride, and sodium bicarbonate). The therapeutic effect of Neohemodez is primarily driven by the ability of low-molecular-weight povidone to bind circulating endogenous and exogenous toxins in the bloodstream, facilitating their rapid renal clearance. Additionally, the solution helps restore water-electrolyte balance, improves capillary microcirculation, reduces erythrocyte stasis, and increases glomerular filtration and diuresis. It is indicated for the treatment of various toxic states, including food poisoning, acute gastrointestinal infections (such as shigellosis and salmonellosis), burn disease, peritonitis, and post-operative or post-traumatic shock.

Brand names
BelvidonGemodez-8000Gemodez8000Gemodez 8000Gemodez-NGemosanKrasgemodez 8000Krasgemodez8000Krasgemodez-8000NeohaemodesNeohemodezSenderesisБелвидонГемодез-8000Гемодез-НГемосанКрасгемодез 8000НеогемодезСендерезис
Other names
calcium chloride + magnesium chloride + potassium chloride + povidone + sodium bicarbonate + sodium chloridecalcium chloride + magnesium chloride + potassium chloride + povidone + sodium hydrogencarbonate + sodium chloridepolyvinylpyrrolidone + sodium chloride + potassium chloride + calcium chloride + magnesium chloride + sodium bicarbonatepolyvinylpyrrolidone + sodium chloride + potassium chloride + calcium chloride + magnesium chloride + sodium hydrogencarbonate

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