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calcium citrate malate + cholecalciferol (Mantecorp Saúde)
- Development stage
- Unknown
- Lead developer
- Mantecorp Saúde
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Addera Cal is a combination nutritional supplement developed by Mantecorp Saúde, a division of Hypera Pharma, primarily indicated for the maintenance of bone health and the prevention or treatment of calcium and vitamin D deficiencies. The formulation contains calcium citrate malate, a highly bioavailable form of calcium that is well-absorbed even in the absence of gastric acid, and cholecalciferol (vitamin D3). Vitamin D3 is essential for the active absorption of calcium from the gastrointestinal tract and for maintaining adequate serum calcium and phosphate concentrations to enable normal mineralization of bone. The product is widely used in Brazil for the prevention and treatment of osteoporosis and osteopenia, particularly in populations at risk for bone density loss.
- Brand names
- Addera Cal
- Other names
- Addera Cal
02
Targets
VDR (Vitamin D receptor)PDIA3 (Membrane-associated rapid response steroid-binding receptor)CaSR (Extracellular calcium-sensing receptor)
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