Drug intelligence / Profile preview

calcium dobesilate + euphorbia prostrata extract

Development stage
Unknown
Lead developer
Janjaes Pharmaceutical
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Ompile is a branded generic medication developed by Janjaes Pharmaceutical, primarily indicated for the management of hemorrhoids. It is marketed in two distinct forms: Ompile Tablets, which contain a combination of the vasoprotective agent calcium dobesilate and a standardized extract of *Euphorbia prostrata* (referred to as Euphorbia Tri Extract), and Ompile Cream, which utilizes herbal ingredients for topical relief. Calcium dobesilate functions by reducing capillary permeability and fragility, improving venous tone, and inhibiting the synthesis of inflammatory mediators like prostaglandins. The *Euphorbia prostrata* extract provides complementary anti-inflammatory, analgesic, and hemostatic properties, helping to reduce bleeding, pain, and swelling associated with internal and external hemorrhoidal disease.

Brand names
Ompile
Other names
Ompile TabletsOmpile Creamcalcium dobesilate + Euphorbia Tri Extract
02

Targets

NF-κBPGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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