calcium hydroxide + silver nanoparticles

A combination medication used primarily in endodontic treatment as an intracanal medicament. This formulation combines the traditional calcium hydroxide with silver nanoparticles to enhance antimicrobial efficacy. Silver nanoparticles provide broad-spectrum antibiofilm action with the ability to reach complex anatomies, while calcium hydroxide serves as a gold standard for root canal disinfection. The combination has shown enhanced effectiveness against various oral pathogens, including bacteria and fungi like Candida albicans, compared to calcium hydroxide alone. Silver nanoparticles exert bactericidal properties by breaking cellular membranes, inhibiting metabolic enzymes, and generating reactive oxygen species.

Other names

Ca(OH)2 + AgNPsCaOHAgNPscalcium hydroxide-coated silver nanoparticles