Drug intelligence / Profile preview

CAM2020 M2SR H3N2 influenza vaccine + Fluzone HD inactivated influenza vaccine

Development stage
Unknown
Lead developer
FluGen
Modality
Vaccines & Immunotherapeutics
Administration
Intranasal, Intramuscular
01

Overview

CAM2020 M2SR H3N2 influenza vaccine + Fluzone HD inactivated influenza vaccine is an investigational combination vaccine regimen being developed by FluGen in collaboration with Sanofi. The regimen consists of FluGen's M2-deficient single-replication (M2SR) intranasal vaccine (specifically the CAM2020 strain derived from A/Cambodia/e0826360/2020) administered alongside Sanofi's Fluzone High-Dose (HD) Quadrivalent, an intramuscular inactivated influenza vaccine. The M2SR component is a live virus vaccine engineered to lack the M2 protein, which allows it to infect host cells and express a broad range of influenza antigens without producing new infectious viral particles. This stimulates both mucosal secretory IgA and cell-mediated immunity. Fluzone HD provides a high-dose systemic antibody response. The combination is designed to enhance protection against influenza in older adults (aged 65-85) by providing both local mucosal and systemic immune responses.

Brand names
Fluzone High-Dose Quadrivalent
Other names
M2SR + Fluzone HDCam2020 M2SR H3N2 + Fluzone HDM2SR + Fluzone High-Dose
02

Targets

HA (Hemagglutinin)Neuraminidase

Beyond the preview

Go deeper on CAM2020 M2SR H3N2 influenza vaccine + Fluzone HD inactivated influenza vaccine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on CAM2020 M2SR H3N2 influenza vaccine + Fluzone HD inactivated influenza vaccine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call