Drug intelligence / Profile preview

camphor + eucalyptol + guaiacol + menthol

Development stage
Unknown
Lead developer
Azidus Brasil
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Topical, Rectal
01

Overview

camphor + eucalyptol + guaiacol + menthol is a combination drug product formulated for relief of cough and upper respiratory tract symptoms, and may also provide temporary relief from minor joint and muscle pain when applied topically. Its components have established pharmacological properties: - **Camphor** acts as a topical analgesic and rubefacient, creating a cooling or warming sensation for local symptom relief and is also a mild counterirritant. - **Eucalyptol** (cineol) is known for its mucolytic and anti-inflammatory activity, and acts primarily in the respiratory tract. - **Guaiacol** is a phenolic compound with expectorant, antiseptic, and mild local anesthetic properties; it scavenges reactive oxygen radicals and may aid cell proliferation. - **Menthol** provides a cooling sensation, suppresses cough reflex via sensory nerve modulation, and exerts mild local analgesic effects. This specific combination is used in rectal (suppository) and topical forms and is intended for symptomatic relief of cough (especially pediatric infectious cough), congestion, and may assist with sleep, nasal obstruction, and general comfort during respiratory illness. The combination acts synergistically to reduce cough and irritation by affecting nerve endings, providing mucolytic effects, and relieving local pain/inflammation[1][2][4][5][6][7].

Brand names
Transpulmin
Other names
camphor, eucalyptol, guaiacol, and menthol suppositorycamphor/eucalyptol/guaiacol/mentholcamphor/eucalyptus oil/menthol
02

Targets

TRPA1 (Transient receptor potential cation channel subfamily A member 1)

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