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camrelizumab + vinorelbine + cisplatin
- Development stage
- Unknown
- Lead developer
- HUTCHMED
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
- Administration
- Intravenous
01
Overview
A combination therapy consisting of the anti-PD-1 antibody camrelizumab and chemotherapy agents vinorelbine and cisplatin. This regimen has been studied as a treatment for relapsed/refractory primary mediastinal B-cell lymphoma (rrPMBCL). In clinical trials, this chemo-immunotherapy combination has shown promising efficacy with a manageable safety profile, particularly for patients with bulky aggressive disease.
02
Targets
TUBB (Tubulin (alpha and beta subunits))DNAPDCD1 (Programmed cell death protein 1 receptor)
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