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cannabidiol + clomiphene
- Development stage
- Preclinical
- Lead developer
- Enveric Biosciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Cannabidiol + clomiphene** is an investigational two-small-molecule anticancer combination described in patents assigned to Jay Pharma. The combination pairs cannabidiol, a non-intoxicating phytocannabinoid, with clomiphene, a selective estrogen receptor modulator and cholesterol-5,6-epoxide hydrolase and antiestrogen-binding-site inhibitor. Patent data describe enhanced growth inhibition and apoptosis in cancer cell models, including HL-60 leukemia and A-172 glioblastoma cells, but no approved or marketed fixed-dose product for this exact combination was identified. ([patentimages.storage.googleapis.com](https://patentimages.storage.googleapis.com/7e/91/ca/003781131fa875/US20180311182A1.pdf))
- Other names
- CBD + clomiphenecannabidiol + clomipheneclomiphene + cannabidiol
02
Targets
ChEH (Cholesterol epoxide hydrolase)ER (Estrogen receptor)
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