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cannabidiol + silicone patch
- Development stage
- Unknown
- Lead developer
- University of Oklahoma
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
This investigational topical formulation consists of cannabidiol (CBD) oil applied in conjunction with a silicone patch. Developed by the University of Oklahoma Health Sciences Center, it is specifically designed to improve scar healing and appearance in adult patients following paramedian forehead flap (PMFF) reconstruction surgery. The active ingredient, cannabidiol, is a non-psychotropic cannabinoid that targets the cannabinoid receptor 2 (CB2). By activating CB2 receptors, the drug aims to reduce inflammation and excessive scar formation while simultaneously promoting skin cell proliferation and wound closure. The product is currently being evaluated in Phase 1 split-scar randomized controlled trials (the TOPSCAR study), where it is compared directly against a standard-of-care silicone patch alone.
- Other names
- Vantage Hemp CBD Isolate + Silicone patchTopical CBD for Paramedian Forehead Flap Scar Healing
02
Targets
CB (Cannabinoid receptors)
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