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Drug intelligence / Profile preview
Cannabis sativa L. 'Afina'
- Development stage
- Phase 2
- Lead developer
- Syqe Medical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Inhalation
01
Overview
Cannabis sativa L. 'Afina' is a standardized medical cannabis cultivar specifically developed for administration via the Syqe Inhaler, a proprietary metered-dose aerosol delivery system. Developed by Syqe Medical, this botanical product is designed to provide precise and consistent dosing of cannabinoids, primarily delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), which are the main active constituents of the 'Afina' strain. The drug is currently being evaluated in Phase IV clinical trials as an add-on therapy for diabetic peripheral neuropathic pain. The Syqe Inhaler technology utilizes thermal decarboxylation of the raw plant material to generate an aerosol, facilitating rapid pulmonary absorption and high bioavailability while minimizing the variability and side effects associated with traditional cannabis consumption methods.
- Brand names
- Afina
- Other names
- medical cannabis aerosol
02
Targets
CNR1 (Cannabinoid receptor 1)
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