Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
CAPOX + modified FOLFOX-7 (Tata Memorial Centre)
- Development stage
- Unknown
- Lead developer
- Tata Memorial Centre
- Modality
- Small Molecules
- Administration
- Oral, Intravenous
01
Overview
CAPOX + modified FOLFOX-7 is a combination chemotherapy strategy used in the treatment of locally advanced rectal cancer, particularly within Total Neoadjuvant Therapy (TNT) protocols. CAPOX consists of capecitabine (an oral prodrug of 5-fluorouracil) and oxaliplatin (a platinum-based antineoplastic agent). Modified FOLFOX-7 is a variation of the FOLFOX regimen comprising oxaliplatin, leucovorin (folinic acid), and 5-fluorouracil (5-FU), typically characterized by the omission of the 5-FU bolus and simplified dosing to reduce toxicity while maintaining efficacy. In the context of rectal cancer, these regimens are used as neoadjuvant or adjuvant systemic therapy to eradicate micrometastases and improve pathological complete response rates when combined with radiation therapy and surgery.
- Other names
- CAPOXmodified FOLFOX-7capecitabine + oxaliplatin + modified FOLFOX-7
02
Targets
TS (Thymidylate synthase)DNA
Beyond the preview
Go deeper on CAPOX + modified FOLFOX-7 (Tata Memorial Centre).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on CAPOX + modified FOLFOX-7 (Tata Memorial Centre).