captopril + hydrochlorothiazide + promethazine

Tianshuping is a fixed-dose combination pharmaceutical preparation developed by West China Hospital, Sichuan University, specifically for the treatment of essential hypertension. It is a well-known hospital-made preparation (院内制剂) in China. The formulation typically consists of captopril, hydrochlorothiazide, and promethazine hydrochloride. Captopril functions as an angiotensin-converting enzyme (ACE) inhibitor, which lowers blood pressure by reducing peripheral vascular resistance. Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water, thereby reducing plasma volume. Promethazine hydrochloride, a first-generation antihistamine with sedative properties, is included in small doses to provide a mild calming effect, which may help manage hypertensive spikes associated with anxiety or stress. This combination leverages multiple physiological pathways to achieve synergistic blood pressure control.

Brand names

Tianshuping

Other names

Compound Captopril TabletsTian Shu Ping天舒平