Carabrone (Nanjing Univ.)

Carabrone (Nanjing Univ.): sourced facts only. name: "Taken together, our results revealed that CA is a novel UBE2D3 inhibitor and provided a promising therapeutic candidate for MS." [PMID:42628619]; target: "Taken together, our results revealed that CA is a novel UBE2D3 inhibitor and provided a promising therapeutic candidate for MS." [PMID:42628619]; developer: "Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China; State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases, Nanjing University, Nanjing, China; Jiangsu Key Laboratory for Molecular Medicine, Medical School of Nanjing University, Nanjing, China." [PMID:42628619]; modality: "Carabrone (CA), a sesquiterpene lactone from the traditional Chinese herb Carpesium abrotanoides L., demonstrates diverse pharmacological properties." [PMID:42628619]; stage: "In the present study, we reported the beneficial effects of CA on experimental autoimmune encephalomyelitis (EAE), a well-established mouse model of MS, for the first time." [PMID:42628619]