Drug intelligence / Profile preview

carbasalate calcium (Royal DSM)

Development stage
Unknown
Lead developer
University Medical Center Utrecht
Modality
Small Molecules
Administration
Oral
01

Overview

Carbasalate calcium is a water-soluble complex of calcium acetylsalicylate and urea that provides acetylsalicylic acid activity. It is an oral salicylate antiplatelet agent: acetylsalicylic acid irreversibly acetylates platelet cyclooxygenase-1, suppressing thromboxane A2 production and thereby reducing platelet aggregation for prevention of arterial thrombotic events. Higher-dose products may also be used for analgesic, antipyretic, and anti-inflammatory effects. Dutch products include Ascal formulations, including 100 mg antiplatelet formulations equivalent to approximately 78.6 mg acetylsalicylic acid. ([pubchem.ncbi.nlm.nih.gov](https://pubchem.ncbi.nlm.nih.gov/compound/Carbaspirin-calcium))

Brand names
AscalAscal CardioAscal Cardio-Neuro
Other names
carbaspirin calciumcalcium carbasalatecarbosalate calciumcalcium acetylsalicylic carbamidatecalcium acetylsalicylate complex with urea
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)

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