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carboplatin + celecoxib + paclitaxel

Development stage: Preclinical
Lead developer: Johnson Matthey
Modality: Small Molecules
Administration: Intravenous, Oral

Overview

This combination involves **carboplatin**, an alkylating agent used to treat various cancers, particularly ovarian cancer; **celecoxib**, a COX-2 inhibitor that may enhance chemosensitivity; and **paclitaxel**, a mitotic inhibitor used in treating cancers like ovarian, breast, and lung cancer. The combination is not a standard branded product but is explored in clinical settings for its potential synergistic effects.

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)DNA

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