Drug intelligence / Profile preview

carboplatin + ixazomib

Development stage
Preclinical
Lead developer
Takeda
Modality
Small Molecules
Administration
Intravenous, Oral
01

Overview

Combination therapy of carboplatin and ixazomib. Carboplatin is an organoplatinum antineoplastic alkylating agent used in various cancer treatments. Ixazomib is a proteasome inhibitor that blocks the ability of cancer cells to reuse certain proteins. The combination is being investigated for efficacy in metastatic triple-negative breast cancer (TNBC) and potentially other cancer types.

02

Targets

DNAPSMB5 (Proteasome subunit beta Type-5)

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