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carboxymethyl-beta-glucan + polycarbophil
- Development stage
- Unknown
- Lead developer
- Effik
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Vaginal
01
Overview
Colpofix is a vaginal gel formulation containing carboxymethyl beta-glucan and polycarbophil, developed for the prevention and treatment of cervical lesions caused by human papillomavirus (HPV). It is classified as a topical medical device that functions through a mucoadhesive mechanism; the polycarbophil component forms a protective film on the cervical mucosa, ensuring prolonged contact for the active ingredients. Carboxymethyl beta-glucan, a chemically modified polysaccharide, acts by modulating the local immune response to facilitate the clearance of HPV infection and the regression of low-grade cervical intraepithelial lesions (CIN1). The product originated in Italy and is marketed by Uriach Consumer Healthcare, with clinical evidence supported by studies involving over 2,000 patients.
- Brand names
- Colpofix
- Other names
- carboxymethyl beta-glucan + polycarbophil
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