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carboxymethylcellulose + glycerin + N-acetylcarnosine
- Development stage
- Unknown
- Lead developer
- Innovative Vision Products
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Peptides, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Ophthalmic
01
Overview
Sionac is an ophthalmic lubricant and antioxidant combination eye drop formulated to relieve dry eyes, ocular irritation, and protect eye tissues from oxidative stress. It contains carboxymethylcellulose sodium (0.3% w/v), glycerin (1% w/v), and N-acetylcarnosine (1% w/v). Carboxymethylcellulose sodium and glycerin act as artificial tears and humectants, providing immediate lubrication, stabilizing the tear film, and protecting the corneal epithelium from hyperosmolar injury. N-acetylcarnosine is a dipeptide antioxidant that penetrates the cornea to neutralize free radicals, helping to protect ocular tissues from oxidative damage and potentially slowing the progression of age-related cataracts. Sionac is marketed by Soviet Pharmaceuticals for the management of dry eye syndrome and overall ocular surface health.
- Brand names
- AquanacArotear PlusC-NacCcs PlusITR PlusLubrinacNature's TearsNice CareNimoist PlusSionacTrotear PlusVisiwet
- Other names
- carboxymethylcellulose + glycerin + n-acetylcarnosinecarboxymethylcellulose sodium + glycerin + N-acetylcarnosinesodium carboxymethylcellulose + glycerin + N-acetylcarnosine
02
Targets
Transition metal ions / redox-active metalsCRY (Crystallin family)
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