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CasInvent CK1 inhibitor (CRC)
- Development stage
- Preclinical
- Lead developer
- CasInvent Pharma
- Modality
- Small Molecules
01
Overview
CasInvent Pharma is developing a selective small-molecule inhibitor of Casein Kinase 1 (CK1) specifically for the treatment of Colorectal Cancer (CRC). Casein Kinase 1 is a family of serine/threonine protein kinases that play a pivotal role in regulating various cellular signaling pathways, most notably the Wnt/beta-catenin pathway, which is frequently dysregulated in colorectal malignancies. By selectively targeting CK1, this therapeutic candidate aims to modulate these oncogenic pathways to suppress tumor growth and progression. The program is currently in the early stages of development as part of CasInvent Pharma's pipeline of CK1-targeted therapies.
- Other names
- Unnamed CRC CandidateCasInvent Pharma-Casein Kinase 1 (CK1)-small molecule-Colorectal Cancer (CRC)CasInvent CK1 inhibitor
02
Targets
CSNK1E (Casein kinase I isoform epsilon)CSNK1D (Casein kinase I delta)CK1α (Casein kinase I alpha)
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