Drug intelligence / Profile preview

Cavit + ferric sulfate

Development stage
Unknown
Lead developer
Virginia Commonwealth University
Modality
Small Molecules
Administration
Topical
01

Overview

Cavit + ferric sulfate is a dental treatment combination being investigated by Virginia Commonwealth University for use in pulpotomy procedures in primary teeth. This approach utilizes a 15.5% ferric sulfate solution as a hemostatic agent to control pulpal bleeding from the pulp stumps, followed by the application of Cavit (a non-eugenol temporary restorative material manufactured by 3M) as a base material. Cavit is composed of zinc oxide, zinc sulfate, and calcium salts, and is known for its excellent sealing capability and induction of an alkaline pH that may promote hard tissue formation. The combination is designed to address the high rate of internal resorption and radiological failure associated with traditional eugenol-containing zinc oxide (ZOE) materials, such as IRM, when used in conjunction with ferric sulfate. By eliminating the release of free eugenol, the treatment aims to provide a more stable environment that avoids the inflammatory responses and failures typically seen in vital pulp therapy in children with pulpitis.

Brand names
Cavit
Other names
non-eugenol based ZOE base material with Ferric Sulfatenon-eugenol zinc oxide + ferric sulfateCavit vs IRM in Ferric Sulfate Pulpotomy

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