Drug intelligence / Profile preview

cefadroxil + clavulanate potassium

Development stage
Unknown
Lead developer
Torrent Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Cefadroxil + clavulanate potassium is an oral combination antibiotic consisting of cefadroxil, a first-generation cephalosporin, and clavulanate potassium, a beta-lactamase inhibitor. Cefadroxil works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs). Clavulanate potassium protects cefadroxil from degradation by certain beta-lactamase enzymes produced by resistant bacteria, thereby extending its spectrum of activity. This combination is primarily used to treat bacterial infections such as urinary tract infections, respiratory tract infections (including pharyngitis, tonsillitis, and pneumonia), and skin and soft tissue infections, particularly those caused by beta-lactamase-producing organisms. It is marketed by companies like Cosmas Pharmaceuticals.

Brand names
Cefadrox-CV
Other names
cefadroxil + potassium clavulanatecefadroxil + clavulanic acid
02

Targets

OAT1 (Organic anion transporter 1)PBP (Penicillin-binding protein family)β-lactamase

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