cefixime + clavulanic acid

Cefixime + clavulanic acid is an oral fixed-dose combination antibiotic consisting of a third-generation cephalosporin and a beta-lactamase inhibitor. Cefixime works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), which leads to cell lysis and death. Clavulanic acid acts as a suicide inhibitor of beta-lactamase enzymes, which are produced by certain bacteria to degrade beta-lactam antibiotics. By neutralizing these enzymes, clavulanic acid prevents the degradation of cefixime, thereby restoring and expanding its spectrum of activity against beta-lactamase-producing organisms. This combination is commonly indicated for the treatment of various bacterial infections, including acute otitis media, respiratory tract infections, and urinary tract infections.

Brand names

Zifi CVCefolac CVMilixim CVTaxim CVCefakind CVHifen CV

Other names

cefixime and potassium clavulanatecefixime + clavulanate