cefixime + ofloxacin (Helax Healthcare)

Cefwell-O is a fixed-dose combination antibiotic product marketed by Helax Healthcare, typically containing cefixime and ofloxacin. Cefixime is a third-generation cephalosporin that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis. Ofloxacin is a fluoroquinolone that inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. This combination is used to treat various bacterial infections, including respiratory tract infections, urinary tract infections, and typhoid fever, providing a broader spectrum of activity against both Gram-positive and Gram-negative pathogens.

Brand names

Cefwell-O

Other names

Cefixime and Ofloxacin Tablets